Garfield

Peter Hewitt

Director

Alan Cumming

Persnikitty (voice)

Michael Monks

Deputy Hopkins

Richard Kind

Dad Rat (voice)

Brad Garrett

Luca (voice)

Jimmy Kimmel

Spanky (voice)

Debra Messing

Arlene (voice)

Stephen Tobolowsky

Happy Chapman

Crystal the Monkey

Pet Monkey (uncredited)

Alyson Stoner

Kid Rat (voice)

Nick Cannon

Louis (voice)

Daamen J. Krall

Announcer

Mel Rodriguez

Security Officer

Mark Christopher Lawrence

Christopher Mello

Bill Murray

Garfield (voice)

Jennifer Love Hewitt

Liz

Breckin Meyer

Jon

Evan Arnold

Wendell

David Eigenberg

Nermal (voice)

Jerry Hauck

Cop

Vanessa Campbell

Miss Ace Hardware

Rufus Gifford

Dog Owner #1

Randee Reicher

Dog Owner #2

Eve Brent

Mrs. Baker

Bill Hoag

Roy the Lodge Member

Susan Moore

Dog Owner #4

Ben Kronen

Older Man

Ryan McKasson

Dog Owner #3

Juliette Goglia

Little Girl

Joseph Edward Taylor

Frank